401 A Change is Gonna Come

written by Shonda Rhimes | directed by Rob Corn | airdate 09.27.07

Having just returned from her honeymoon with Meredith, Cristina searches for Burke, but he's nowhere to be found. Meredith, Cristina, Izzie and Alex spend their first day as residents with their own groups of interns – among the interns are George, repeating his intern year after failing his exams, and Lexie Grey, Meredith's half-sister whom she has never met. Now that Derek's relationship with Meredith has reached an emotional impasse, he looks to his fellow doctors for friendship; Bailey wrestles with her place within the hospital now that her former interns report to new Chief Resident Callie; and Richard resumes his position as Chief of Surgery.

< Previous Episode | Grey's Anatomy Season Four Home | Next Episode >

Round-Up: “A Change is Gonna Come”

ABC.com Recap show After failing his exam, George reluctantly faces his first day reliving his internship among a sea of fresh faces. Meanwhile, Cristina, Meredith, Izzie and Alex are in charge of their own interns and George is assigned to Meredith. Neither Cristina or Meredith have heard from her exes since the wedding, and they [...]